Immunodiagnostics is the standard against which many agent detection, identification, and diagnostic technologies are compared. Antibody-based assays continue to serve as preliminary and confirmatory diagnostic formats for many infectious and non-infectious diseases. The increasing need for consistently high-quality immunodiagnostic reagents for biothreat agents and the difficulty of producing sufficient quantities safely in biocontainment makes recombinant antigens and antibodies the ideal solution. The ultimate goal of this scientific effort is to provide not only high-quality reagents for existing assays, but to develop a system that can quickly produce reagents to new and emerging biothreat agents. This program is presented by Dr. Randal Schoepp, chief of the Applied Diagnostics Branch in the Diagnostic Systems Division, at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).